- Home
- Trimix Shot Clinic
Trimix Shot Clinic

Trimix is a compounded, injectable medication used to treat erectile dysfunction (ED) in men who do not respond well to oral medications such as Viagra or Cialis. It is a combination of three drugs: alprostadil, phentolamine, and papaverine, which work synergistically to increase blood flow to the penis, leading to an erection.
How Does Trimix Work?
Each component of Trimix plays a unique role in improving erectile function:
- Alprostadil (Prostaglandin E1): A vasodilator that relaxes smooth muscle tissue and dilates blood vessels.
- Phentolamine: Blocks certain neurotransmitters that cause blood vessel constriction, enhancing blood flow.
- Papaverine: A muscle relaxant that promotes prolonged blood flow to erectile tissue.
By combining these three ingredients, Trimix offers a potent alternative to oral ED treatments, often producing a more reliable and stronger erection.
Who Can Benefit from Trimix?
Trimix injections are particularly beneficial for men with:
- Severe erectile dysfunction unresponsive to oral medications.
- Diabetes-related ED.
- Post-prostatectomy ED.
- ED caused by vascular conditions.
How to Use Trimix Injections
Trimix is administered through an intracavernosal injection, meaning it is injected directly into the penile tissue. Here’s a step-by-step guide on how to use it safely:
- Preparation: Wash hands and sterilize the injection site with alcohol.
- Dosage: Draw the prescribed dose into an insulin syringe.
- Injection: Insert the needle into the side of the penis, avoiding veins.
- Massage: Lightly massage the area to help distribute the medication.
- Wait: An erection typically occurs within 5–15 minutes and lasts 30 minutes to an hour.
Potential Side Effects
While Trimix is generally effective, some users may experience:
- Mild pain at the injection site.
- Prolonged erections (priapism) lasting over 4 hours, which requires medical attention.
- Penile fibrosis (scar tissue development) with frequent use.
- Bruising or minor bleeding.
Precautions and Safety Tips
- Only use the prescribed dose to avoid priapism.
- Rotate injection sites to prevent tissue damage.
- Store Trimix as directed (often refrigerated).
- Seek immediate medical help if an erection lasts longer than 4 hours.
Conclusion
Trimix injections are a powerful and effective solution for men with erectile dysfunction who have not found success with oral medications. With proper usage and guidance from a healthcare provider, Trimix can significantly enhance sexual function and improve quality of life.